Modified Nucleosides
4-Thiothymidine
Quick view. A 2'-deoxythymidine nucleoside in which the pyrimidine C4 carbonyl oxygen is replaced by sulfur. CAS 7236-57-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
4-Thiothymidine is classified as 4-thio-2'-deoxythymidine nucleoside (Formula C10H14N2O4S; molecular weight 258.30 g/mol).
4-Thiothymidine is associated with thymidine-containing building blocks or substrates for DNA synthesis and analytical comparison.
For 4-Thiothymidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 4-Thiodeoxythymidine
- Deoxy-4-thiothymidine
- 4-Thio-D-thymidine
Useful catalog search terms
- 7236-57-9
- AVKSPBJBGGHUMW-XLPZGREQSA-N
Physicochemical data
| PubChem CID | 3034569 |
|---|---|
| IUPAC name | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-4-sulfanylidenepyrimidin-2-one |
| InChIKey | AVKSPBJBGGHUMW-XLPZGREQSA-N |
| SMILES | CC1=CN(C(=O)NC1=S)[C@H]2C[C@@H]([C@H](O2)CO)O |
| InChI | InChI=1S/C10H14N2O4S/c1-5-3-12(10(15)11-9(5)17)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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