Linker Phosphoramidites
5'-Maleimide-Modifier Phosphoramidite
Quick view. 5'-Maleimide-Modifier Phosphoramidite is a protected maleimide phosphoramidite identified by CAS 1316303-83-9 for oligonucleotide synthesis research. CAS 1316303-83-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-Maleimide-Modifier Phosphoramidite is classified as linker phosphoramidites (Formula C21H32N3O5P; molecular weight 437.47).
5'-Maleimide-Modifier Phosphoramidite — Reference use: introduction of a protected 5' maleimide functionality during oligonucleotide synthesis for subsequent thiol conjugation studies.
For 5'-Maleimide-Modifier Phosphoramidite, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- CAS 1316303-83-9
- C21H32N3O5P
- Glen 10-1938
Physicochemical data
| Product-form boundary | Protected maleimide Diels-Alder adduct; distinct from the post-retro-Diels-Alder maleimide |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-Maleimide-Modifier Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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