Modified Nucleosides
5-Methyl-4-thiouridine
Quick view. A stereodefined uridine nucleoside bearing methyl at base C5 and sulfur at base C4. CAS 49555-43-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5-Methyl-4-thiouridine is classified as c5-methyl c4-thio uridine nucleoside (Formula C10H14N2O5S; molecular weight 274.30 g/mol).
5-Methyl-4-thiouridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5-Methyl-4-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- 49555-43-3
- IXDWFVOGUMAKFI-JXOAFFINSA-N
Physicochemical data
| PubChem CID | 56613468 |
|---|---|
| IUPAC name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-4-sulfanylidenepyrimidin-2-one |
| InChIKey | IXDWFVOGUMAKFI-JXOAFFINSA-N |
| InChI | InChI=1S/C10H14N2O5S/c1-4-2-12(10(16)11-8(4)18)9-7(15)6(14)5(3-13)17-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,18)/t5-,6-,7-,9-/m1/s1 |
| SMILES | CC1=CN(C(=O)NC1=S)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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