Halogenated Nucleosides
5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine
Quick view. A 5'-O-DMTr-protected 5-iodouridine building block for structure-specific protected nucleoside and nucleotide synthesis research. CAS 158728-68-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine is classified as halogenated nucleosides (Formula C30H29IN2O8; molecular weight 672.46).
5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine — 5'-O-DMTr-protected 5-iodouridine building block for structure-specific protected nucleoside and nucleotide synthesis research.
For 5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-5-I-U
- 5'-DMT-5-I-U
- 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-iodouridine
Useful catalog search terms
- CAS 158728-68-8
Physicochemical data
| Systematic designation | 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione |
|---|---|
| Nucleobase modification | 5-iodo |
| Protecting group | 5'-O-(4,4'-dimethoxytrityl) |
| InChIKey | GOLQPGCNIAQGQO-IYUNARRTSA-N |
| InChI | InChI=1S/C30H29IN2O8/c1-38-21-12-8-19(9-13-21)30(18-6-4-3-5-7-18,20-10-14-22(39-2)15-11-20)40-17-24-25(34)26(35)28(41-24)33-16-23(31)27(36)32-29(33)37/h3-16,24-26,28,34-35H,17H2,1-2H3,(H,32,36,37)/t24-,25-,26-,28-/m1/s1 |
| SMILES | COC1=CC=C(C=C1)C(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(C(=C1)I)=O)=O)O)O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC |
| Canonical SMILES | COC1=CC=C(C=C1)C(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(C(=C1)I)=O)=O)O)O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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