Halogenated Nucleosides
7-Deaza-2',3'-dideoxy-7-iodoguanosine
Quick view. 7-Deaza-2',3'-dideoxy-7-iodoguanosine is a 7-iodo-7-deazaguanosine nucleoside bearing a 2',3'-dideoxy sugar, with CAS 114748-67-3. CAS 114748-67-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
7-Deaza-2',3'-dideoxy-7-iodoguanosine is classified as 7-iodo-7-deaza-2',3'-dideoxyguanosine nucleoside (Formula C11H13IN4O3; molecular weight 376.15).
7-Deaza-2',3'-dideoxy-7-iodoguanosine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For 7-Deaza-2',3'-dideoxy-7-iodoguanosine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 7-Iodo-7-deaza-2',3'-dideoxyguanosine
- 7-Iodo-7-deaza-dideoxyguanosine
Useful catalog search terms
- CAS 114748-67-3
Physicochemical data
| MDL number | MFCD28139111 |
|---|---|
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=C(C3=C2N=C(NC3=O)N)I |
| Structural feature | 7-deaza/7-iodo base with 2',3'-dideoxy sugar |
| PubChem CID | 135577906 |
| InChIKey | KJNOBXXCZQLWLF-CAHLUQPWSA-N |
| InChI | InChI=1S/C11H13IN4O3/c12-6-3-16(7-2-1-5(4-17)19-7)9-8(6)10(18)15-11(13)14-9/h3,5,7,17H,1-2,4H2,(H3,13,14,15,18)/t5-,7+/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 7-Deaza-2',3'-dideoxy-7-iodoguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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