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Sulfurizing Reagents

Beaucage Reagent

Quick view. A benzodithiole sulfur-transfer reagent used in the sulfurization step for phosphorothioate oligonucleotide synthesis. CAS 66304-01-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.

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Chemical structure of Beaucage reagent
Chemical structure
Catalog numberOR-SR-0003
CAS number66304-01-6
PurityBy inquiry
Pack sizeCustom packaging by inquiry

Product profile

Material identity

Beaucage Reagent is classified as sulfurizing reagents (Formula C7H4O3S2; molecular weight 200.23).

Typical application

Beaucage Reagent — Sulfurization step for formation of phosphorothioate linkages in oligonucleotide synthesis workflows.

Handling focus

For Beaucage Reagent, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

PubChem CID3009847
InChIKeyJUDOLRSMWHVKGX-UHFFFAOYSA-N
Systematic name3H-1,2-Benzodithiol-3-one 1,1-dioxide
Reagent classBenzodithiole sulfur-transfer reagent
InChIInChI=1S/C7H4O3S2/c8-7-5-3-1-2-4-6(5)12(9,10)11-7/h1-4H
SMILESC1=CC=C2C(=C1)C(=O)SS2(=O)=O

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Product-relevant literature

The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.