Phosphorus Reagents
Bis[2-(trimethylsilyl)ethyl] N,N-diisopropylphosphoramidite
Quick view. A bis(trimethylsilylethyl)-protected P(III) phosphoramidite reagent for oligonucleotide-related phosphitylation research. CAS 121373-20-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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![Chemical structure of Bis[2-(trimethylsilyl)ethyl] N,N-diisopropylphosphoramidite](/structures/6126ce031fb2f357.svg)
Product profile
Bis[2-(trimethylsilyl)ethyl] N,N-diisopropylphosphoramidite is classified as phosphorus reagents (Formula C16H40NO2PSi2; molecular weight 365.64).
Bis[2-(trimethylsilyl)ethyl] N,N-diisopropylphosphoramidite — Phosphitylation reagent for preparation of oligonucleotide-related intermediates
For Bis[2-(trimethylsilyl)ethyl] N,N-diisopropylphosphoramidite, storage: 2-8 C; protect from light and store under nitrogen. Form: Liquid.
Names and search terms
Confirmed or normalized name variants
- Bis(2-(trimethylsilyl)ethyl) diisopropylphosphoramidite
- iPr2N-P-(OTSE)2
Useful catalog search terms
- 121373-20-4
- OTSE phosphoramidite
Physicochemical data
| InChIKey | UCVPTNNSVPPRRA-UHFFFAOYSA-N |
|---|---|
| SMILES | CC(C)N(C(C)C)P(OCC[Si](C)(C)C)OCC[Si](C)(C)C |
| Form | Liquid |
| Density | 0.8887 g/mL at 25 C |
| Boiling Point | 286.2-296.6 C |
| Refractive Index | 1.4517 |
| PubChem CID | 11760300 |
| InChI | InChI=1S/C16H40NO2PSi2/c1-15(2)17(16(3)4)20(18-11-13-21(5,6)7)19-12-14-22(8,9)10/h15-16H,11-14H2,1-10H3 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Introduction of trimethylsilylethyl-protected phosphate functionality
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Product-family literature
These publications provide peer-reviewed context for the Phosphorus Reagents product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.