2'-O-Me Phosphoramidites
5'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine-3'-(L)-PSM phosphoramidite
Quick view. A stereodefined L-PSM phosphoramidite of 5'-O-DMTr, 2'-O-methyl, N2-isobutyrylguanosine for oligonucleotide synthesis research. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
5'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine-3'-(L)-PSM phosphoramidite is classified as 2'-o-me phosphoramidites (Formula C48H53N6O11PS; molecular weight 953.02).
5'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine-3'-(L)-PSM phosphoramidite — Protected stereodefined L-PSM guanosine phosphoramidite monomer for oligonucleotide synthesis research.
For 5'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine-3'-(L)-PSM phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- DMTr-2'-O-Me-rG(iBu)-3'-(L)-PSM-Phosphoramidite
- DMT-2'-O-Me-rG(iBu)-3'-(L)-PSM phosphoramidite
Useful catalog search terms
- QCPFOYJTUFIVGR-JADAPZILSA-N
Physicochemical data
| InChIKey | QCPFOYJTUFIVGR-JADAPZILSA-N |
|---|---|
| Nucleoside | 5'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine |
| Chiral auxiliary | (L)-PSM cyclic phosphoramidite |
| Stereochemical boundary | Reagent stereochemistry defined; final linkage outcome not asserted |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine-3'-(L)-PSM phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
4'-O-[(Dimethoxyphosphoryl)methyl]-2'-O-methyluridine-3'-CE-Phosphoramidite
2'-O-Me Phosphoramidites · CAS: 2197181-94-3
OR-2OMP-00164'-O-[(Hydroxy(methoxy)phosphoryl)methyl]-2'-O-methyluridine-3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)
2'-O-Me Phosphoramidites · CAS: N/A
OR-2OMP-00175'-Deoxy-5'-[(dimethoxyphosphoryl)methyl]-2'-O-methyluridine-3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)
2'-O-Me Phosphoramidites · CAS: N/A
OR-2OMP-0019Bis(POM)-(E)-5'-vinylphosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite
2'-O-Me Phosphoramidites · CAS: 2419895-65-9
OR-2OMP-0020Bis(POM)-(E)-5'-vinylphosphonate-2'-O-Me-rC(Bz)-3'-CE-Phosphoramidite
2'-O-Me Phosphoramidites · CAS: N/A
OR-2OMP-0021Bis(POM)-(E)-5'-vinylphosphonate-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite
2'-O-Me Phosphoramidites · CAS: N/A
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.