RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite is an N6-benzoyl- and 2'-O-TBDMS-protected adenosine building block for research-use RNA oligonucleotide synthesis. CAS 104992-55-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite is classified as protected riboadenosine phosphoramidite (Formula C53H66N7O8PSi; molecular weight 988.20).
DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite — N6-benzoyl- and 2'-O-TBDMS-protected adenosine phosphoramidite building block for research-use RNA oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Bz-rA Phosphoramidite
- 2'-TBDMS-A CEP
- DMT-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite
Useful catalog search terms
- 104992-55-4
- PubChem 11355126
- C53H66N7O8PSi
- Sigma A211000
- Areterna PA008
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Base protection | N6-benzoyl |
|---|---|
| Ribose protection | 2'-O-TBDMS |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | FFXHNCNNHASXCT-RFMFGJHUSA-N |
| InChI | InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1 |
| SMILES | COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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