DNA Phosphoramidites
DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite
Quick view. DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite is a TIPS-protected 5-ethynyl-deoxyuridine building block for research-use solid-phase oligonucleotide synthesis. CAS 1472616-97-9. Catalog target purity: 99%+. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite is classified as protected modified deoxyuridine phosphoramidite (Formula C50H67N4O8PSi; molecular weight 911.16).
DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite — TIPS-protected 5-ethynyl-deoxyuridine phosphoramidite building block for research-use solid-phase oligonucleotide synthesis.
For DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- TIPS-5-Ethynyl-dU-CE phosphoramidite
- DMT-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite
Useful catalog search terms
- 1472616-97-9
- C50H67N4O8PSi
- ONT1472616979
- HR-00206020
- DNA Phosphoramidites
Physicochemical data
| Protection state | 5'-DMTr and TIPS-protected 5-ethynyl group |
|---|---|
| Coupling group | 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| Physical form | White to off-white powder |
| Water content reference | ≤0.5% |
| InChIKey | CCVQXLLQYFTKGP-KSJPBEHZSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.