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TNA Phosphoramidites

DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite

Quick view. DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite is a protected TNA guanine phosphoramidite building block identified by CAS 325683-97-4 for research-use oligonucleotide synthesis. CAS 325683-97-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.

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Chemical structure of DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite
Chemical structure
Catalog numberOR-TNA-0003
CAS number325683-97-4
PurityBy inquiry
Pack size200 mg; 1 g; 5 g; Custom packaging by inquiry

Product profile

Material identity

DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite is classified as tna phosphoramidites (Formula C54H57N8O9P; molecular weight 993.10).

Typical application

DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite — Protected TNA guanine phosphoramidite building block for research-use oligonucleotide synthesis.

Handling focus

For DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite, storage: -20 C.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

InChIKeyQGLNDUMJEPXLMP-DMYMLFOFSA-N
Stereochemistry2R,3R,4S; phosphorus configuration unspecified
Protecting groupsDMTr; O6-diphenylcarbamoyl; N2-acetyl
Coupling group2-Cyanoethyl N,N-diisopropyl phosphoramidite
Physical formSolid
PubChem CID101221383
InChIInChI=1S/C54H57N8O9P/c1-36(2)62(37(3)4)72(68-33-17-32-55)71-48-46(70-54(39-18-11-8-12-19-39,40-24-28-44(65-6)29-25-40)41-26-30-45(66-7)31-27-41)34-67-51(48)60-35-56-47-49(60)58-52(57-38(5)63)59-50(47)69-53(64)61(42-20-13-9-14-21-42)43-22-15-10-16-23-43/h8-16,18-31,35-37,46,48,51H,17,33-34H2,1-7H3,(H,57,58,59,63)/t46-,48+,51+,72?/m0/s1
SMILESCC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](CO[C@H]1N2C=NC3=C2N=C(N=C3OC(=O)N(C4=CC=CC=C4)C5=CC=CC=C5)NC(=O)C)OC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Product-family literature

These publications provide peer-reviewed context for the TNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.