Other Phosphoramidites
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rT-3'-oxy)-bis(diisopropylphosphoramidite)
Quick view. A symmetric bis(phosphoramidite) containing two 5'-O-DMTr-2'-O-MOE thymidine units connected through an ethane-1,2-diyl linker. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rT-3'-oxy)-bis(diisopropylphosphoramidite) is classified as ethane-1,2-linked thymidine bis(phosphoramidite).
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rT-3'-oxy)-bis(diisopropylphosphoramidite) — Bis(phosphoramidite) building block for research-use oligonucleotide synthesis.
For ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rT-3'-oxy)-bis(diisopropylphosphoramidite), mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Physicochemical data
| Nucleoside units | Two thymidine units |
|---|---|
| 5' protection | DMTr |
| 2' substituent | 2-methoxyethyl |
| Phosphoramidite centers | Two diisopropylphosphoramidite groups |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rT-3'-oxy)-bis(diisopropylphosphoramidite) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Other Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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