Modified Nucleosides
N1-Ethylpseudouridine
Quick view. N1-Ethylpseudouridine is an N1-alkylated pseudouridine for research-use modified-nucleoside chemistry. CAS 1613529-72-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N1-Ethylpseudouridine is classified as n1-alkylated pyrimidine c-nucleoside (Formula C11H16N2O6; molecular weight 272.25).
N1-Ethylpseudouridine — An N1-ethylated pseudouridine for research-use modified-nucleoside and oligonucleotide chemistry.
For N1-Ethylpseudouridine, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Confirmed or normalized name variants
- 1-Ethylpseudouridine
- 1-Ethyl-5-beta-D-ribofuranosylpyrimidine-2,4-dione
Useful catalog search terms
- CAS 1613529-72-8
Physicochemical data
| PubChem CID | 90220440 |
|---|---|
| InChIKey | AMMRPAYSYYGRKP-BGZDPUMWSA-N |
| Modification | ethyl substituent at pseudouridine N1 |
| InChI | InChI=1S/C11H16N2O6/c1-2-13-3-5(10(17)12-11(13)18)9-8(16)7(15)6(4-14)19-9/h3,6-9,14-16H,2,4H2,1H3,(H,12,17,18)/t6-,7-,8-,9+/m1/s1 |
| SMILES | CCN1C=C(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
These points describe N1-Ethylpseudouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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