Protected Nucleosides
N2-Isobutyryl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)guanosine
Quick view. An N2-isobutyryl- and 5'-O-dimethoxytrityl-protected 3'-deoxyguanosine intermediate for structure-specific nucleoside and phosphoramidite route development. CAS 157327-99-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N2-Isobutyryl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)guanosine is classified as protected nucleosides (Formula C35H37N5O7; molecular weight 639.70).
N2-Isobutyryl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)guanosine — Protected 3'-deoxyguanosine intermediate for structure-specific nucleoside and phosphoramidite route development.
For N2-Isobutyryl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)guanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- CAS 157327-99-6
- PubChem CID 146503055
Physicochemical data
| PubChem CID | 146503055 |
|---|---|
| InChIKey | RJDSSRLUDDDCHK-QSOCVKKASA-N |
| IUPAC name | N-[9-[(2R,3R,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide |
| SMILES | CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H](C[C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O |
| Sugar modification | 3'-deoxy |
| Protecting groups | N2-isobutyryl; 5'-O-dimethoxytrityl |
| InChI | InChI=1S/C35H37N5O7/c1-21(2)31(42)38-34-37-30-29(32(43)39-34)36-20-40(30)33-28(41)18-27(47-33)19-46-35(22-8-6-5-7-9-22,23-10-14-25(44-3)15-11-23)24-12-16-26(45-4)17-13-24/h5-17,20-21,27-28,33,41H,18-19H2,1-4H3,(H2,37,38,39,42,43)/t27-,28+,33+/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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