DNA / Phosphoramidites
N4-Benzoyl-3'-O-DMTr-2'-deoxycytidine 5'-CE phosphoramidite
Quick view. An N4-benzoyl-protected deoxycytidine reverse phosphoramidite bearing 3'-O-DMTr and a 5'-O-CE phosphoramidite group, CAS 140712-83-0. CAS 140712-83-0. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Reviewed supporting program count | 1 |
| Representative chemistry-platform program | onvuzosiran |
| Highest development phase | Phase III |
| CAS status | Published registry number |
Product profile
N4-Benzoyl-3'-O-DMTr-2'-deoxycytidine 5'-CE phosphoramidite is classified as dna / phosphoramidites (Formula C46H52N5O8P; molecular weight 833.90).
N4-Benzoyl-3'-O-DMTr-2'-deoxycytidine 5'-CE phosphoramidite — A 5'-CE reverse deoxycytidine phosphoramidite building block for research-use oligonucleotide synthesis.
For N4-Benzoyl-3'-O-DMTr-2'-deoxycytidine 5'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- DMT-dC(Bz)-CE Reverse Phosphoramidite
- DMT-dC(Bz)-5'-CE Reverse Phosphoramidite
- N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite
Useful catalog search terms
- 140712-83-0
- PB09087
- OXUQZHDIUOKQGM-SALLYJDFSA-N
- PubChem CID 15403759
Physicochemical data
| SMILES | CC(C)N(C(C)C)P(OCCC#N)OC[C@@H]1[C@H](C[C@@H](O1)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)OC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC |
|---|---|
| Synthesis orientation | Reverse (5'-O-CE phosphoramidite) |
| 3' protection | DMTr |
| Base protection | N4-benzoyl |
| Sugar | 2'-Deoxyribose |
| PubChem CID | 15403759 |
| InChIKey | OXUQZHDIUOKQGM-SALLYJDFSA-N |
| InChI | InChI=1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(56-29-13-27-47)57-31-41-40(30-43(58-41)50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)59-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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