GalNAc
L96 Block 1 (DMT-Protected Pyrrolidine Linker Acid)
Quick view. L96 Block 1 is a DMT-protected chiral pyrrolidine linker acid with a terminal carboxylic acid and free secondary alcohol for research-use staged scaffold functionalization. CAS 1159408-70-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
L96 Block 1 (DMT-Protected Pyrrolidine Linker Acid) is classified as dmt-protected chiral pyrrolidine linker acid (Formula C38H49NO7; molecular weight 631.80).
L96 Block 1 (DMT-Protected Pyrrolidine Linker Acid) — DMT-protected chiral pyrrolidine linker acid for research-use staged L96 scaffold functionalization.
For L96 Block 1 (DMT-Protected Pyrrolidine Linker Acid), in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- L96 Block 1
- G1-20
- (3R,5S)-5-O-DMT-3-pyrrolidinol-12-oxododecanoic acid
- Peracetylated GalNAc-L96-Acid-2
Useful catalog search terms
- DMT-protected pyrrolidine linker acid
- HR-01006008
- 1159408-70-4
- C38H49NO7
Physicochemical data
| Protected functionality | Hydroxymethyl group as DMT ether |
|---|---|
| Exposed handles | Terminal carboxylic acid and secondary alcohol |
| Appearance | White to light yellow powder |
| InChIKey | CEYLTMDXADTBEL-JHOUSYSJSA-N |
| PubChem CID | 57874622 |
| InChI | InChI=1S/C38H49NO7/c1-44-34-22-18-30(19-23-34)38(29-14-10-9-11-15-29,31-20-24-35(45-2)25-21-31)46-28-32-26-33(40)27-39(32)36(41)16-12-7-5-3-4-6-8-13-17-37(42)43/h9-11,14-15,18-25,32-33,40H,3-8,12-13,16-17,26-28H2,1-2H3,(H,42,43)/t32-,33+/m0/s1 |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4C[C@H](CN4C(=O)CCCCCCCCCCC(=O)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe L96 Block 1 (DMT-Protected Pyrrolidine Linker Acid) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the GalNAc product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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