GalNAc
Peracetylated GalNAc Pentaamide-C3
Quick view. Peracetylated GalNAc Pentaamide-C3 is the unsalted free-base form of a protected GalNAc amino-linker identified by CAS 1637413-94-5. CAS 1637413-94-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
Peracetylated GalNAc Pentaamide-C3 is classified as peracetylated galnac amino-linker intermediate (Formula C22H37N3O10; molecular weight 503.55).
Peracetylated GalNAc Pentaamide-C3 can be used when comparing GalNAc ligand/linker architecture for liver-targeted oligonucleotide conjugation research.
For Peracetylated GalNAc Pentaamide-C3, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- GalNAc-pentaamide-C3
- Peracetylated GalNAc-L96-Amide-1
- (2R,3R,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-((5-((3-aminopropyl)amino)-5-oxopentyl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate
Useful catalog search terms
- 1637413-94-5
- 142489227
- DMJVSLQIPZGUTN-MIUGBVLSSA-N
Physicochemical data
| PubChem CID | 142489227 |
|---|---|
| Systematic name | (2R,3R,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-((5-((3-aminopropyl)amino)-5-oxopentyl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate |
| SMILES | CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1OCCCCC(=O)NCCCN)COC(=O)C)OC(=O)C)OC(=O)C |
| InChIKey | DMJVSLQIPZGUTN-MIUGBVLSSA-N |
| Chemical form | Free base |
| Functional groups | Terminal primary amine; amide; peracetylated GalNAc |
| InChI | InChI=1S/C22H37N3O10/c1-13(26)25-19-21(34-16(4)29)20(33-15(3)28)17(12-32-14(2)27)35-22(19)31-11-6-5-8-18(30)24-10-7-9-23/h17,19-22H,5-12,23H2,1-4H3,(H,24,30)(H,25,26)/t17-,19-,20+,21-,22-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe Peracetylated GalNAc Pentaamide-C3 or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the GalNAc product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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