OROGO PRODUCT CATEGORY
2'-Fluoro Phosphoramidites
Quick view. 2′-fluoro nucleoside phosphoramidites for modified RNA, siRNA and stability-focused oligonucleotide studies. This category currently includes 22 products. 2'-Fluoro Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
Category guide
2'-Fluoro Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.
Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.
Product-family considerations
- Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
- Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
- Common ribose modifications can improve nuclease resistance and modulate RNA-like binding behavior.
- Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
- Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.
Category literature
These publications provide background for the 2'-Fluoro Phosphoramidites product family. Individual product pages only show additional product- or feature-relevant references.
Selection checklist
| Exact identity | Match the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable. |
|---|---|
| Specification | Define target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits. |
| Workflow fit | Share the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility. |
| Supply need | Provide initial quantity, expected future scale, packaging preference, timeline and documentation requirements. |
Product comparison
This snapshot compares up to eight products in the current catalog order. It uses published catalog fields only; confirm the exact form, pack size, specification and current availability by inquiry.
Swipe or scroll horizontally to compare all fields.
| Product name | OR catalog no. | CAS | Purity / specification | Supply status | Chemical class |
|---|---|---|---|---|---|
| DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite | OR-2FP-0022 | 2227139-97-9 | By inquiry | Inquiry only | L-DPSE 2'-fluoro guanosine phosphoramidite |
| DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-Phosphoramidite | OR-2FP-0023 | 1528733-99-4 | By inquiry | Inquiry only | L-DPSE 2'-fluoro adenosine phosphoramidite |
| DMTr-2'-F-dU-3'-CE-Phosphoramidite | OR-2FP-0024 | 146954-75-8 | By inquiry | Inquiry only | 2'-fluoro-2'-deoxyuridine phosphoramidite |
| DMTr-2'-F-dC(Ac)-3'-CE-Phosphoramidite | OR-2FP-0025 | 159414-99-0 | By inquiry | Inquiry only | Protected 2'-fluoro-2'-deoxycytidine phosphoramidite |
| DMTr-2'-F-dA(Bz)-3'-CE-Phosphoramidite | OR-2FP-0026 | 136834-22-5 | By inquiry | Inquiry only | Protected 2'-fluoro-2'-deoxyadenosine phosphoramidite |
| DMTr-2'-F-dG(iBu)-3'-CE-Phosphoramidite | OR-2FP-0027 | 144089-97-4 | By inquiry | Inquiry only | Protected 2'-fluoro-2'-deoxyguanosine phosphoramidite |
| DMTr-2'-F-dC(Bz)-3'-CE-Phosphoramidite | OR-2FP-0028 | 161442-19-9 | By inquiry | Inquiry only | Protected 2'-fluoro-2'-deoxycytidine phosphoramidite |
| DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite | OR-2FP-0002 | 1528734-00-0 | By inquiry | Inquiry only | Protected 2'-fluoro deoxyadenosine D-DPSE phosphoramidite |
22 products
DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-PhosphoramiditeBy inquiry · CAS: 2227139-97-9
OR-2FP-0022
DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-PhosphoramiditeBy inquiry · CAS: 1528733-99-4
OR-2FP-0023
DMTr-2'-F-dU-3'-CE-PhosphoramiditeBy inquiry · CAS: 146954-75-8
OR-2FP-0024
DMTr-2'-F-dC(Ac)-3'-CE-PhosphoramiditeBy inquiry · CAS: 159414-99-0
OR-2FP-0025
DMTr-2'-F-dA(Bz)-3'-CE-PhosphoramiditeBy inquiry · CAS: 136834-22-5
OR-2FP-0026
DMTr-2'-F-dG(iBu)-3'-CE-PhosphoramiditeBy inquiry · CAS: 144089-97-4
OR-2FP-0027
DMTr-2'-F-dC(Bz)-3'-CE-PhosphoramiditeBy inquiry · CAS: 161442-19-9
OR-2FP-0028
DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-PhosphoramiditeBy inquiry · CAS: 1528734-00-0
OR-2FP-0002
2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramiditeBy inquiry · CAS: 2245842-16-2
OR-2FP-0021
DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-PhosphoramiditeBy inquiry · CAS: 2227140-01-2
OR-2FP-0007
DMTr-2'-F-dT-3'-CE-PhosphoramiditeBy inquiry · CAS: 182700-06-7
OR-2FP-0009
DMTr-2'-F-dU-3'-(D)-DPSE-PhosphoramiditeBy inquiry · CAS: 1528734-09-9
OR-2FP-0010
DMTr-2'-F-dU-3'-(L)-DPSE-PhosphoramiditeBy inquiry · CAS: 1528734-08-8
OR-2FP-0011
DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-PhosphoramiditeBy inquiry · CAS: 3055727-89-1
OR-2FP-0012
DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-PhosphoramiditeBy inquiry · CAS: N/A
OR-2FP-0001
DMTr-2'-F-dG(dmf)-3'-(L)-PSM-PhosphoramiditeBy inquiry · CAS: N/A
OR-2FP-0005
DMTr-2'-F-dG(dmf)-3'-CE-PhosphoramiditeBy inquiry · CAS: 3081868-42-7
OR-2FP-0006
DMTr-2'-F-dG(iBu)-3'-(L)-PSM-PhosphoramiditeBy inquiry · CAS: N/A
OR-2FP-0008
DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-PhosphoramiditeBy inquiry · CAS: N/A
OR-2FP-0003
DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-PhosphoramiditeBy inquiry · CAS: N/A
OR-2FP-0004
N4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramiditeBy inquiry · CAS: 182495-83-6
OR-2FP-0032
MMTr-2'-F-dG(iBu)-3'-CE phosphoramiditeBy inquiry · CAS: N/A
OR-2FP-0014Frequently asked questions
What are typical uses for 2'-Fluoro Phosphoramidites?
2'-Fluoro Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
What should be confirmed before ordering 2'-Fluoro Phosphoramidites?
Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.
Are custom quantities or related analogs available?
OROGO reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.
Need help selecting a product?
Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.