Modified Nucleosides
2',3'-O-Isopropylidene-5-hydroxyuridine
Quick view. 5-Hydroxyuridine derivative with the ribose 2'- and 3'-oxygen atoms joined by an isopropylidene acetal and a free 5'-hydroxyl. CAS 20406-82-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-O-Isopropylidene-5-hydroxyuridine is classified as modified nucleosides (Formula C12H16N2O7; molecular weight 300.26 g/mol).
2',3'-O-Isopropylidene-5-hydroxyuridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2',3'-O-Isopropylidene-5-hydroxyuridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Isopropylidene-5-hydroxyuridine
- 5-Hydroxy-2',3'-O-(1-methylethylidene)uridine
Useful catalog search terms
- 20406-82-0
Physicochemical data
| Nucleobase modification | Uracil C5 hydroxyl |
|---|---|
| Sugar protection | Cyclic 2',3'-O-isopropylidene acetal |
| Hydroxyl state | 5' hydroxyl unprotected |
| InChIKey | PFQQRJQXCGDITH-FDDDBJFASA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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