Modified Nucleosides
2,8-Dimethyladenosine
Quick view. A 2,8-dimethyl-substituted adenosine derivative identified by CAS 63954-66-5 and the modified-nucleoside abbreviation m2,8A. CAS 63954-66-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2,8-Dimethyladenosine is classified as modified nucleosides (Formula C12H17N5O4; molecular weight 295.29).
2,8-Dimethyladenosine — Referenced in RNA-modification research as the product formed when Cfr methylates position 2 of 8-methyladenosine.
For 2,8-Dimethyladenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- m2,8A
Useful catalog search terms
- CAS 63954-66-5
Physicochemical data
| Systematic name | (2R,3R,4S,5R)-2-(6-amino-2,8-dimethylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
|---|---|
| Isomeric SMILES | CC1=NC(=C2C(=N1)N(C(=N2)C)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N |
| PubChem CID | 101784714 |
| InChI | InChI=1S/C12H17N5O4/c1-4-14-10(13)7-11(15-4)17(5(2)16-7)12-9(20)8(19)6(3-18)21-12/h6,8-9,12,18-20H,3H2,1-2H3,(H2,13,14,15)/t6-,8-,9-,12-/m1/s1 |
| InChIKey | FGMBEEFIKCGALL-WOUKDFQISA-N |
| SMILES | CC1=NC(=C2C(=N1)N(C(=N2)C)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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