2'-O-Me Nucleosides
2'-O-Methyl-7-deazaadenosine
Quick view. A 2'-O-methyl-7-deazaadenosine nucleoside building block for nucleoside and oligonucleotide synthesis research. CAS 68345-70-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-O-Methyl-7-deazaadenosine is classified as 2'-o-me nucleosides (Formula C12H16N4O4; molecular weight 280.28).
2'-O-Methyl-7-deazaadenosine — Modified purine nucleoside building block for nucleoside and oligonucleotide synthesis research.
For 2'-O-Methyl-7-deazaadenosine, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Me-7-deaza-rA
- 2'-O-methyltubercidin
Useful catalog search terms
- CAS 68345-70-0
Physicochemical data
| InChIKey | WCONFZNVYYZVNH-MFYTUXHUSA-N |
|---|---|
| Nucleobase | 7-Deazaadenine |
| Sugar modification | 2'-O-methyl |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-O-Methyl-7-deazaadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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