Protected Nucleosides
2'-O-TBDMS-5-methyluridine
Quick view. A 5-methyluridine derivative protected at the 2'-hydroxyl with a tert-butyldimethylsilyl group. CAS 922508-26-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
2'-O-TBDMS-5-methyluridine is classified as protected nucleosides (Formula C16H28N2O6Si; molecular weight 372.49 g/mol (calculated from formula)).
2'-O-TBDMS-5-methyluridine — 2'-O-silyl-protected 5-methyluridine intermediate for downstream nucleoside chemistry.
For 2'-O-TBDMS-5-methyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O-[tert-Butyl(dimethyl)silyl]-5-methyluridine
- 2'-TBDMS-5-Me-rU
Useful catalog search terms
- 922508-26-7
- PWAAFDSCYLYFMA-HKUMRIAESA-N
Physicochemical data
| InChIKey | PWAAFDSCYLYFMA-HKUMRIAESA-N |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O[Si](C)(C)C(C)(C)C |
| Nucleoside | 5-Methyluridine |
| Protected position | 2'-O |
| Protecting group | tert-Butyldimethylsilyl (TBDMS) |
| InChI | InChI=1S/C16H28N2O6Si/c1-9-7-18(15(22)17-13(9)21)14-12(11(20)10(8-19)23-14)24-25(5,6)16(2,3)4/h7,10-12,14,19-20H,8H2,1-6H3,(H,17,21,22)/t10-,11-,12-,14-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
2'-O-TBDMS-rG(iBu)
Protected Nucleosides · CAS: 182007-86-9
OR-PN-00435'-O-DMTr-2'-O-TBDMS-rC(Ac)
Protected Nucleosides · CAS: 121058-85-3
OR-PN-00575'-O-TBDMS-3'-O-TBDMS-5-(hydroxymethyl)-dC
Protected Nucleosides · CAS: 1257247-39-4
OR-PN-00585'-O-TBDMS-3'-O-TBDMS-5-I-dC
Protected Nucleosides · CAS: 478843-96-8
OR-PN-00673'-O-TBDMS-2'-F-dG(iBu)
Protected Nucleosides · CAS: 2382967-92-0
OR-PN-00683'-O-TBDMS-2'-F-dA(Bz)
Protected Nucleosides · CAS: 1244763-25-4
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.