Imetelstat Series Phosphoramidites
3'-NH-Trt-2',3'-ddA(dmf)-5'-CE-Phosphoramidite
Quick view. A protected 3'-amino-2',3'-dideoxyadenosine building block bearing 3'-N-trityl and N6-dimethylformamidine protection with a 5'-O-CE diisopropylphosphoramidite group. CAS 1644649-86-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
3'-NH-Trt-2',3'-ddA(dmf)-5'-CE-Phosphoramidite is classified as imetelstat series phosphoramidites (Formula C41H50N9O3P; molecular weight 747.90).
3'-NH-Trt-2',3'-ddA(dmf)-5'-CE-Phosphoramidite is supplied for research use within the Imetelstat Series Phosphoramidites product family.
For 3'-NH-Trt-2',3'-ddA(dmf)-5'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2-Cyanoethyl (((2S,3S,5R)-5-(6-(((dimethylamino)methylene)amino)-9H-purin-9-yl)-3-(tritylamino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite
Useful catalog search terms
- CAS 1644649-86-4
Physicochemical data
| Protection pattern | 3'-N-trityl; N6-dimethylformamidine; 5'-O-CE diisopropylphosphoramidite |
|---|---|
| Sugar stereochemistry | (2S,3S,5R) in the PubChem title representation |
| Phosphorus stereochemistry | Unspecified |
| InChIKey | GYBKIQYITQGOTA-BJTKYJPYSA-N |
| PubChem CID | 168441300 |
| InChI | InChI=1S/C41H50N9O3P/c1-30(2)50(31(3)4)54(51-24-16-23-42)52-26-36-35(25-37(53-36)49-29-45-38-39(46-28-48(5)6)43-27-44-40(38)49)47-41(32-17-10-7-11-18-32,33-19-12-8-13-20-33)34-21-14-9-15-22-34/h7-15,17-22,27-31,35-37,47H,16,24-26H2,1-6H3/b46-28+/t35-,36+,37+,54?/m0/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)OC[C@@H]1[C@H](C[C@@H](O1)N2C=NC3=C(N=CN=C32)/N=C/N(C)C)NC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
3'-NH-Trt-2',3'-ddC(Bz)-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 195375-65-6
OR-ISP-00033'-NH-Trt-2',3'-ddG(iBu)-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 195375-66-7
OR-ISP-00043'-NH-Trt-2',3'-ddT-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 195375-68-9
OR-ISP-00053'-NH-Trt-2',3'-ddA(Bz)-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 195375-64-5
Product-family literature
These publications provide peer-reviewed context for the Imetelstat Series Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.