Modified Nucleosides
5-Carboxymethyluridine
Quick view. Uridine derivative bearing a carboxymethyl substituent at the 5-position of the pyrimidine ring. CAS 20964-06-1. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5-Carboxymethyluridine is classified as modified nucleosides (Formula C11H14N2O8; molecular weight 302.24 g/mol).
5-Carboxymethyluridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5-Carboxymethyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- 5-(Carboxymethyl)uridine
- 20964-06-1
Physicochemical data
| Base scaffold | Uridine |
|---|---|
| Base modification | 5-carboxymethyl |
| Protection state | Unprotected |
| InChIKey | FAWQJBLSWXIJLA-VPCXQMTMSA-N |
| InChI | InChI=1S/C11H14N2O8/c14-3-5-7(17)8(18)10(21-5)13-2-4(1-6(15)16)9(19)12-11(13)20/h2,5,7-8,10,14,17-18H,1,3H2,(H,15,16)(H,12,19,20)/t5-,7-,8-,10-/m1/s1 |
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)CC(=O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5-Carboxymethyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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