GalNAc
5'-GalNAc C3 Phosphoramidite
Quick view. 5'-GalNAc C3 Phosphoramidite is a TMT-protected GalNAc C3 phosphoramidite building block for research-use 5'-terminal oligonucleotide modification. CAS 2437303-51-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-GalNAc C3 Phosphoramidite is classified as tmt-protected galnac c3 phosphoramidite (Formula C62H88N5O17P; molecular weight 1206.40).
5'-GalNAc C3 Phosphoramidite — TMT-protected GalNAc C3 phosphoramidite building block for research-use 5'-terminal oligonucleotide modification.
For 5'-GalNAc C3 Phosphoramidite, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- GalNAc C3 Amidite
Useful catalog search terms
- 5'-GalNAc-C3 Phosphoramidite
- HR-01006005
- 2437303-51-8
- C62H88N5O17P
- GalNAc
Physicochemical data
| Protecting group | Trimethoxytrityl (TMT) |
|---|---|
| Coupling group | 2-Cyanoethyl N,N-diisopropyl phosphoramidite |
| Appearance | White to light yellow powder |
| PubChem CID | 170903051 |
| InChI | InChI=1S/C62H88N5O17P/c1-42(2)67(43(3)4)85(80-38-16-33-63)81-41-61(40-79-62(48-19-25-51(74-9)26-20-48,49-21-27-52(75-10)28-22-49)50-23-29-53(76-11)30-24-50)31-35-66(36-32-61)56(73)18-13-12-14-34-64-55(72)17-15-37-77-60-57(65-44(5)68)59(83-47(8)71)58(82-46(7)70)54(84-60)39-78-45(6)69/h19-30,42-43,54,57-60H,12-18,31-32,34-41H2,1-11H3,(H,64,72)(H,65,68)/t54-,57-,58+,59-,60-,85?/m1/s1 |
| InChIKey | CBVYXTMIYQCOPE-KDYLSCEUSA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)OCC1(CCN(CC1)C(=O)CCCCCNC(=O)CCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C)COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe 5'-GalNAc C3 Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.