Modified Nucleosides
5-Hydroxymethyluridine
Quick view. A uridine nucleoside bearing a hydroxymethyl substituent at the 5-position of the pyrimidine ring. CAS 30414-00-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5-Hydroxymethyluridine is classified as 5-substituted uridine nucleoside (Formula C10H14N2O7; molecular weight 274.23 g/mol).
5-Hydroxymethyluridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5-Hydroxymethyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- 5-Hydroxymethyl uridine
- 30414-00-7
- VQAJJNQKTRZJIQ-JXOAFFINSA-N
Physicochemical data
| PubChem CID | 121698 |
|---|---|
| IUPAC name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione |
| InChIKey | VQAJJNQKTRZJIQ-JXOAFFINSA-N |
| InChI | InChI=1S/C10H14N2O7/c13-2-4-1-12(10(18)11-8(4)17)9-7(16)6(15)5(3-14)19-9/h1,5-7,9,13-16H,2-3H2,(H,11,17,18)/t5-,6-,7-,9-/m1/s1 |
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)CO |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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