Protected Nucleosides
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine
Quick view. A uridine derivative bearing 5'-O-(4,4'-dimethoxytrityl) and 3'-O-tert-butyldimethylsilyl protecting groups, identified by CAS 81246-81-3. CAS 81246-81-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine is classified as protected nucleosides (Formula C36H44N2O8Si; molecular weight 660.80).
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMTr-3'-O-TBDMS-uridine
Useful catalog search terms
- CAS 81246-81-3
- PubChem CID 14375994
Physicochemical data
| PubChem CID | 14375994 |
|---|---|
| InChIKey | ZATGYRPVDYINRF-WXQJYUTRSA-N |
| Nucleoside | uridine |
| Sugar protection | 5'-O-DMTr; 3'-O-TBDMS |
| Hydroxyl state | free 2' hydroxyl |
| InChI | InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-29(45-33(31(32)40)38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13-17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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