2'-FANA Nucleosides
8-Chloro-2'-deoxy-2'-fluoroarabinoadenosine
Quick view. 8-Chloro-2'-deoxy-2'-fluoroarabinoadenosine is listed for research-use inquiry under 2'-FANA Nucleosides. Its identity is controlled by the retained exact structure and product-form evidence because no public CAS Registry Number is assigned. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
8-Chloro-2'-deoxy-2'-fluoroarabinoadenosine is classified as 2'-fana nucleosides (Formula C10H11ClFN5O3; molecular weight 303.68).
8-Chloro-2'-deoxy-2'-fluoroarabinoadenosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 8-Chloro-2'-deoxy-2'-fluoroarabinoadenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Physicochemical data
| CAS status | No public CAS assigned |
|---|---|
| Identity control | Reviewed exact name, structure, and product form |
| Covalent InChIKey | RHTNRUHTRGZHIP-AYQXTPAHSA-N |
| Covalent InChI | InChI=1S/C10H11ClFN5O3/c11-10-16-5-7(13)14-2-15-8(5)17(10)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,14,15)/t3-,4+,6-,9-/m1/s1 |
| Covalent SMILES | Nc1ncnc2c1nc(Cl)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F |
| Canonical covalent SMILES | Nc1ncnc2c1nc(Cl)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 8-Chloro-2'-deoxy-2'-fluoroarabinoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.