Modified Nucleosides
8-Hydroxymethylguanosine
Quick view. A guanosine ribonucleoside bearing a hydroxymethyl substituent at the 8-position of the purine base. CAS 54898-41-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
8-Hydroxymethylguanosine is classified as c8-substituted guanosine nucleoside (Formula C11H15N5O6; molecular weight 313.27 g/mol).
8-Hydroxymethylguanosine is associated with guanine-containing building blocks or substrates for G-position incorporation and analytical comparison.
For 8-Hydroxymethylguanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- 8-Hydroxymethyl guanosine
- 54898-41-8
- 135779019
- PQGSVCVISXGQOL-KAFVXXCXSA-N
Physicochemical data
| PubChem CID | 135779019 |
|---|---|
| IUPAC name | 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-(hydroxymethyl)-1H-purin-6-one |
| InChIKey | PQGSVCVISXGQOL-KAFVXXCXSA-N |
| InChI | InChI=1S/C11H15N5O6/c12-11-14-8-5(9(21)15-11)13-4(2-18)16(8)10-7(20)6(19)3(1-17)22-10/h3,6-7,10,17-20H,1-2H2,(H3,12,14,15,21)/t3-,6-,7-,10-/m1/s1 |
| SMILES | C([C@@H]1[C@H]([C@H]([C@@H](O1)N2C(=NC3=C2N=C(NC3=O)N)CO)O)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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