Cap Analogs
m7G(5')ppp(5')(2'-OMeG) ammonium salt
Quick view. A dinucleotide Cap1 analogue in variable ammonium form for in-vitro RNA transcription and cap-analogue research. CAS 57718-00-0 and the listed composition refer to the free acid. CAS 57718-00-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
m7G(5')ppp(5')(2'-OMeG) ammonium salt is classified as cap analogs.
m7G(5')ppp(5')(2'-OMeG) ammonium salt — Cap1-related in-vitro RNA transcription and cap-analogue research.
For m7G(5')ppp(5')(2'-OMeG) ammonium salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP m7G(5')ppp(5')(2'OMeG) Ammonium Salt
- m7GpppGm ammonium salt
- M7-GpppG(2'OMe) ammonium salt
- BRP-00649
Useful catalog search terms
- CAS 57718-00-0
Physicochemical data
| Related CAS | 57718-00-0 (free acid) |
|---|---|
| Counterion form | Ammonium salt; stoichiometry variable |
| Nucleotide shorthand | m7G(5')ppp(5')(2'-OMeG) |
| Free-acid molecular formula | C22H31N10O18P3 |
| Formula basis | Free-acid form |
| Free-acid molecular weight | 816.46 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe m7G(5')ppp(5')(2'-OMeG) ammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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OR-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
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OR-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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