2'-O-Me Phosphoramidites
5'-O-DMTr-2'-O-Me-6-[3-(3-methoxy-3-oxopropyl)phenyl]purine riboside-3'-CE-Phosphoramidite
Quick view. A 5'-O-DMTr, 2'-O-methyl purine riboside CE phosphoramidite bearing a C6-linked 3-(3-methoxy-3-oxopropyl)phenyl group for oligonucleotide synthesis research. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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![Chemical structure of 5'-O-DMTr-2'-O-Me-6-[3-(3-methoxy-3-oxopropyl)phenyl]purine riboside-3'-CE-Phosphoramidite](/structures/7eb5b6e0ca0e826a.jpg)
Product profile
5'-O-DMTr-2'-O-Me-6-[3-(3-methoxy-3-oxopropyl)phenyl]purine riboside-3'-CE-Phosphoramidite is classified as 2'-o-me phosphoramidites (Formula C51H59N6O9P; molecular weight 931.04).
5'-O-DMTr-2'-O-Me-6-[3-(3-methoxy-3-oxopropyl)phenyl]purine riboside-3'-CE-Phosphoramidite — Structurally defined 2'-O-methyl modified purine phosphoramidite building block for oligonucleotide synthesis research.
For 5'-O-DMTr-2'-O-Me-6-[3-(3-methoxy-3-oxopropyl)phenyl]purine riboside-3'-CE-Phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- DMTr-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite
Useful catalog search terms
- C51H59N6O9P
- UYFASKQCDQCXQQ-MREAKBAOSA-N
Physicochemical data
| InChIKey | UYFASKQCDQCXQQ-MREAKBAOSA-N |
|---|---|
| Purine substituent | C6-linked 3-(3-methoxy-3-oxopropyl)phenyl |
| Ribose modification | 2'-O-methyl |
| Coupling group | 3'-CE phosphoramidite |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5'-O-DMTr-2'-O-Me-6-[3-(3-methoxy-3-oxopropyl)phenyl]purine riboside-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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