Modified Nucleotides
N1-Methylpseudouridine-5'-triphosphate trisodium salt
Quick view. A trisodium N1-methylpseudouridine triphosphate solution for modified-mRNA synthesis research. CAS 3056945-59-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N1-Methylpseudouridine-5'-triphosphate trisodium salt is classified as modified nucleotides (Formula C10H14N2Na3O15P3; molecular weight 564.11).
N1-Methylpseudouridine-5'-triphosphate trisodium salt — Nucleobase-modified UTP reagent for modified-mRNA synthesis research
For N1-Methylpseudouridine-5'-triphosphate trisodium salt, form: Aqueous solution.
Names and search terms
Confirmed or normalized name variants
- N1-Me-Pseudo UTP trisodium
- N1-Methyl-Pseudo-UTP trisodium
- 1-Methylpseudouridine-5'-triphosphate trisodium
Useful catalog search terms
- N1-Methylpseudouridine-5'-triphosphate trisodium
- 3056945-59-3
- NHPNEQMMDVBDAB-PBGPPWEJSA-K
- PubChem CID 168267072
Physicochemical data
| Free-acid CAS | 1428903-59-6 |
|---|---|
| Form | Aqueous solution |
| Color | Colorless to light yellow |
| Solution concentration | 100 mM |
| Storage temperature | -80 C for the reviewed MCE trisodium format |
| PubChem CID | 168267072 |
| InChIKey | NHPNEQMMDVBDAB-PBGPPWEJSA-K |
| InChI | InChI=1S/C10H17N2O15P3.3Na/c1-12-2-4(9(15)11-10(12)16)8-7(14)6(13)5(25-8)3-24-29(20,21)27-30(22,23)26-28(17,18)19;;;/h2,5-8,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19);;;/q;3*+1/p-3/t5-,6-,7-,8+;;;/m1.../s1 |
| SMILES | CN1C=C(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+] |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
These points describe N1-Methylpseudouridine-5'-triphosphate trisodium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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