Protected Nucleosides
N2-[2-(4-Isopropylphenoxy)acetyl]-2'-O-propargylguanosine
Quick view. Guanosine derivative bearing an N2-[2-(4-isopropylphenoxy)acetyl] group and a 2'-O-propargyl sugar modification. CAS 2095417-23-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N2-[2-(4-Isopropylphenoxy)acetyl]-2'-O-propargylguanosine is classified as protected nucleosides (Formula C24H27N5O7; molecular weight 497.51 g/mol).
N2-[2-(4-Isopropylphenoxy)acetyl]-2'-O-propargylguanosine is useful as a bioorthogonal handle for post-synthetic conjugation to fluorophores, affinity tags, surfaces, peptides or other functional payloads.
For N2-[2-(4-Isopropylphenoxy)acetyl]-2'-O-propargylguanosine, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine
Useful catalog search terms
- 2095417-23-3
Physicochemical data
| Nucleoside | Guanosine |
|---|---|
| N2 substitution | 2-(4-isopropylphenoxy)acetyl |
| 2' modification | O-propargyl |
| InChIKey | HXWQCQDIIINIIH-UGTJMOTHSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe N2-[2-(4-Isopropylphenoxy)acetyl]-2'-O-propargylguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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