Protected Nucleosides
N4-Benzoyl-3'-O-methylcytidine
Quick view. A cytidine derivative bearing N4-benzoyl protection and a 3'-O-methyl sugar modification, identified by CAS 85079-03-4. CAS 85079-03-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N4-Benzoyl-3'-O-methylcytidine is classified as protected nucleosides (Formula C17H19N3O6; molecular weight 361.35).
N4-Benzoyl-3'-O-methylcytidine can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For N4-Benzoyl-3'-O-methylcytidine, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- Cytidine, N-benzoyl-3'-O-methyl-
Useful catalog search terms
- CAS 85079-03-4
Physicochemical data
| InChIKey | HBJGWSUTFFOKLJ-XKVFNRALSA-N |
|---|---|
| Nucleoside | cytidine |
| Base protection | N4-benzoyl |
| Sugar modification | 3'-O-methyl |
| Free hydroxyls | 2'-OH and 5'-OH |
| PubChem CID | 153757347 |
| InChI | InChI=1S/C17H19N3O6/c1-25-14-11(9-21)26-16(13(14)22)20-8-7-12(19-17(20)24)18-15(23)10-5-3-2-4-6-10/h2-8,11,13-14,16,21-22H,9H2,1H3,(H,18,19,23,24)/t11-,13-,14-,16-/m1/s1 |
| SMILES | CO[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe N4-Benzoyl-3'-O-methylcytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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