Halogenated Nucleosides
N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine
Quick view. Adenosine derivative bearing N6-(3-trifluoromethylbenzyl) and 2'-C-methyl substituents. CAS 2305415-78-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine is classified as halogenated nucleosides (Formula C19H20F3N5O4; molecular weight 439.39 g/mol).
N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 2305415-78-3
Physicochemical data
| Nucleoside | Adenosine |
|---|---|
| Substitution pattern | N6-(3-trifluoromethylbenzyl); 2'-C-methyl |
| InChIKey | XASOSWGKKYFVTP-AXYPVASZSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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