Protected Nucleosides
2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine
Quick view. A uridine derivative bearing 2'-O- and 3'-O-tert-butyldimethylsilyl groups together with 5'-O-(4,4'-dimethoxytrityl) protection, identified by CAS 82444-76-6. CAS 82444-76-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine is classified as protected nucleosides (Formula C42H58N2O8Si2; molecular weight 775.10).
2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2',3'-Bis-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)uridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Bis-O-TBDMS-5'-O-DMTr-uridine
Useful catalog search terms
- CAS 82444-76-6
- PubChem CID 168437207
Physicochemical data
| PubChem CID | 168437207 |
|---|---|
| InChIKey | HBLOFQAJPFGIEN-DOVDTPAYSA-N |
| Nucleoside | uridine |
| Sugar protection | 2'-O-TBDMS; 3'-O-TBDMS; 5'-O-DMTr |
| Hydroxyl state | no free ribose hydroxyl represented |
| InChI | InChI=1S/C42H58N2O8Si2/c1-40(2,3)53(9,10)51-36-34(50-38(44-27-26-35(45)43-39(44)46)37(36)52-54(11,12)41(4,5)6)28-49-42(29-16-14-13-15-17-29,30-18-22-32(47-7)23-19-30)31-20-24-33(48-8)25-21-31/h13-27,34,36-38H,28H2,1-12H3,(H,43,45,46)/t34-,36-,37-,38-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C)C(C)(C)C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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