2'-FANA Nucleosides
2'-Deoxy-2'-fluoro-beta-D-arabinouridine
Quick view. 2'-Deoxy-2'-fluoro-beta-D-arabinouridine is a 2'-fluoro-arabino nucleoside building block for research-use FANA nucleoside and oligonucleotide chemistry. CAS 69123-94-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-Deoxy-2'-fluoro-beta-D-arabinouridine is classified as 2'-fana nucleoside (Formula C9H11FN2O5; molecular weight 246.19).
2'-Deoxy-2'-fluoro-beta-D-arabinouridine — A 2'-fluoro-arabino uridine building block for research-use FANA nucleoside and oligonucleotide chemistry.
For 2'-Deoxy-2'-fluoro-beta-D-arabinouridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-FANA-dU
- 2'-Fluoro-2'-deoxy-arabinouridine
- 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
- 2'-Deoxy-2'-fluoro-ara-uridine
- 2'-deoxy-2'-fluoro-arabino-uridine
Useful catalog search terms
- CAS 69123-94-0
- OR-2FN-0074
- OR-2FAN-0039
- OR-2FAN-0043
Physicochemical data
| PubChem CID | 3007908 |
|---|---|
| InChIKey | UIYWFOZZIZEEKJ-PXBUCIJWSA-N |
| Modification | fluorine at the arabinofuranose 2'-position |
| InChI | InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6+,7-,8-/m1/s1 |
| SMILES | C1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoro-beta-D-arabinouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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