Modified Nucleosides
3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine
Quick view. 3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine is a doubly TBDPS-protected thymidine derivative with CAS 118068-35-2. CAS 118068-35-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine is classified as silyl-protected thymidine nucleoside (Formula C42H50N2O5Si2; molecular weight 719.05).
3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine is associated with thymidine-containing building blocks or substrates for DNA synthesis and analytical comparison.
For 3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Thymidine, 3',5'-bis-O-[(1,1-dimethylethyl)diphenylsilyl]-
- Wikidata Q90540793
Useful catalog search terms
- CAS 118068-35-2
Physicochemical data
| Structural feature | tert-Butyldiphenylsilyl ethers at 3' and 5' |
|---|---|
| PubChem CID | 10556813 |
| InChI | InChI=1S/C42H50N2O5Si2/c1-31-29-44(40(46)43-39(31)45)38-28-36(49-51(42(5,6)7,34-24-16-10-17-25-34)35-26-18-11-19-27-35)37(48-38)30-47-50(41(2,3)4,32-20-12-8-13-21-32)33-22-14-9-15-23-33/h8-27,29,36-38H,28,30H2,1-7H3,(H,43,45,46)/t36-,37+,38+/m0/s1 |
| InChIKey | OCFYNDLJERQLMN-YXWIYCFASA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO[Si](C3=CC=CC=C3)(C4=CC=CC=C4)C(C)(C)C)O[Si](C5=CC=CC=C5)(C6=CC=CC=C6)C(C)(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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