TIPDS-protected Nucleosides
3',5'-O-TIPDS-rU
Quick view. 3',5'-O-TIPDS-rU is uridine protected by a 3',5'-O-TIPDS bridge, leaving the 2'-hydroxyl unprotected. CAS 69304-38-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3',5'-O-TIPDS-rU is classified as tipds-protected nucleosides (Formula C21H38N2O7Si2; molecular weight 486.70).
3',5'-O-TIPDS-rU — Protected uridine intermediate for research route development involving the free 2'-hydroxyl.
For 3',5'-O-TIPDS-rU, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3',5'-O-TIPDS-uridine
- 3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine
Useful catalog search terms
- CAS 69304-38-7
Physicochemical data
| Protecting-group pattern | 3',5'-O-TIPDS bridge |
|---|---|
| Unprotected position | 2'-hydroxyl |
| Encoded stereochemistry | (6aR,8R,9R,9aS) |
| Systematic name | 1-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]pyrimidine-2,4-dione |
| InChIKey | KKLQDUCRZCCKHG-VBSBHUPXSA-N |
| InChI | InChI=1S/C21H38N2O7Si2/c1-12(2)31(13(3)4)27-11-16-19(29-32(30-31,14(5)6)15(7)8)18(25)20(28-16)23-10-9-17(24)22-21(23)26/h9-10,12-16,18-20,25H,11H2,1-8H3,(H,22,24,26)/t16-,18-,19-,20-/m1/s1 |
| SMILES | CC(C)[Si]1(OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=O)NC3=O)O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the TIPDS-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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