Imetelstat Series Phosphoramidites
3'-NH-Trt-2',3'-ddA(Bz)-5'-CE-Phosphoramidite
Quick view. A protected 3'-amino-2',3'-dideoxyadenosine building block bearing N6-benzoyl and 3'-N-trityl protection with a 5'-O-CE diisopropylphosphoramidite group. CAS 195375-64-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-NH-Trt-2',3'-ddA(Bz)-5'-CE-Phosphoramidite is classified as imetelstat series phosphoramidites (Formula C45H49N8O4P; molecular weight 796.90).
3'-NH-Trt-2',3'-ddA(Bz)-5'-CE-Phosphoramidite is supplied for research use within the Imetelstat Series Phosphoramidites product family.
For 3'-NH-Trt-2',3'-ddA(Bz)-5'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- ((2S,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-3-(tritylamino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
Useful catalog search terms
- CAS 195375-64-5
Physicochemical data
| Protection pattern | N6-benzoyl; 3'-N-trityl; 5'-O-CE diisopropylphosphoramidite |
|---|---|
| Sugar stereochemistry | (2S,3S,5R) in the PubChem title representation |
| Phosphorus stereochemistry | Unspecified |
| InChIKey | WFMJBNBVXHQESI-YWGGCHKGSA-N |
| PubChem CID | 10557285 |
| InChI | InChI=1S/C45H49N8O4P/c1-32(2)53(33(3)4)58(55-27-17-26-46)56-29-39-38(51-45(35-20-11-6-12-21-35,36-22-13-7-14-23-36)37-24-15-8-16-25-37)28-40(57-39)52-31-49-41-42(47-30-48-43(41)52)50-44(54)34-18-9-5-10-19-34/h5-16,18-25,30-33,38-40,51H,17,27-29H2,1-4H3,(H,47,48,50,54)/t38-,39+,40+,58?/m0/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)OC[C@@H]1[C@H](C[C@@H](O1)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)NC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
3'-NH-Trt-2',3'-ddA(dmf)-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 1644649-86-4
OR-ISP-00023'-NH-Trt-2',3'-ddC(Bz)-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 195375-65-6
OR-ISP-00033'-NH-Trt-2',3'-ddG(iBu)-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 195375-66-7
OR-ISP-00043'-NH-Trt-2',3'-ddT-5'-CE-Phosphoramidite
Imetelstat Series Phosphoramidites · CAS: 195375-68-9
Product-family literature
These publications provide peer-reviewed context for the Imetelstat Series Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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