Modified Nucleosides
4'-Thiouridine
Quick view. A ribose-modified uridine in which sulfur replaces the furanose ring oxygen at the 4' position, identified by CAS 6741-73-7. CAS 6741-73-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
4'-Thiouridine is classified as modified nucleosides (Formula C9H12N2O5S; molecular weight 260.27).
Route intermediate for protected 4'-thiouridine building blocks used in oligonucleotide synthesis research.
For 4'-Thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 4'-Thioribosyluridine
- 1-(4'-Thio-beta-ribofuranosyl)uracil
Useful catalog search terms
- CAS 6741-73-7
- PubChem CID 11219149
Physicochemical data
| Sugar modification | 4'-thio ribofuranose |
|---|---|
| Isomeric SMILES | C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](S2)CO)O)O |
| InChIKey | MUSPKJVFRAYWAR-XVFCMESISA-N |
| PubChem CID | 11219149 |
| InChI | InChI=1S/C9H12N2O5S/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 |
| SMILES | C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](S2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Substrate for 4'-thionucleoside diversification studies.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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