Intermediates
5-Fluorouracil-1-yl acetic acid
Quick view. A 5-fluorouracil derivative bearing an acetic acid substituent at the pyrimidine N1 position. CAS 56059-30-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5-Fluorouracil-1-yl acetic acid is classified as 5-fluorouracil n1-acetic acid derivative (Formula C6H5FN2O4; molecular weight 188.11 g/mol).
5-Fluorouracil-1-yl acetic acid — Reported in patent literature as a prepared intermediate for further conjugate synthesis.
For 5-Fluorouracil-1-yl acetic acid, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2-(5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid
Useful catalog search terms
- 56059-30-4
- CPMUSDZOVZYEJJ-UHFFFAOYSA-N
Physicochemical data
| InChIKey | CPMUSDZOVZYEJJ-UHFFFAOYSA-N |
|---|---|
| PubChem CID | 1378560 |
| InChI | InChI=1S/C6H5FN2O4/c7-3-1-9(2-4(10)11)6(13)8-5(3)12/h1H,2H2,(H,10,11)(H,8,12,13) |
| SMILES | C1=C(C(=O)NC(=O)N1CC(=O)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5-Fluorouracil-1-yl acetic acid or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.