Sugars
5-O-(Dimethoxytrityl)-1,2-dideoxy-D-ribose
Quick view. A cyclic 1,4-anhydro deoxyribose derivative bearing a dimethoxytrityl-protected hydroxymethyl group. CAS 95049-01-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5-O-(Dimethoxytrityl)-1,2-dideoxy-D-ribose is classified as sugars (Formula C26H28O5; molecular weight 420.50 g/mol).
5-O-(Dimethoxytrityl)-1,2-dideoxy-D-ribose — DMTr-protected deoxyribose building block for downstream nucleoside and modified-sugar chemistry.
For 5-O-(Dimethoxytrityl)-1,2-dideoxy-D-ribose, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 1,2-Dideoxy-5-O-DMT-D-ribose
- 1,4-Anhydro-5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-D-erythro-pentitol
- (2R,3S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-ol
Useful catalog search terms
- 95049-01-7
- C26H28O5
Physicochemical data
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](CCO4)O |
|---|---|
| InChIKey | ZUNGTVUTOQJPDE-LOSJGSFVSA-N |
| Physical form | Solid |
| Sugar scaffold | 1,4-Anhydro-1,2-dideoxy-D-ribose |
| Protecting group | Dimethoxytrityl (DMTr) |
| PubChem CID | 13845246 |
| InChI | InChI=1S/C26H28O5/c1-28-22-12-8-20(9-13-22)26(19-6-4-3-5-7-19,21-10-14-23(29-2)15-11-21)31-18-25-24(27)16-17-30-25/h3-15,24-25,27H,16-18H2,1-2H3/t24-,25+/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 5-O-(Dimethoxytrityl)-1,2-dideoxy-D-ribose or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Sugars product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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