Intermediates
7-Aminomethyl-7-deazaguanine dihydrochloride
Quick view. The dihydrochloride salt of 7-aminomethyl-7-deazaguanine (preQ1), identified by CAS 86694-45-3. CAS 86694-45-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
7-Aminomethyl-7-deazaguanine dihydrochloride is classified as intermediates (Formula C7H11Cl2N5O; molecular weight 252.10).
7-Aminomethyl-7-deazaguanine dihydrochloride provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 7-Aminomethyl-7-deazaguanine dihydrochloride, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- preQ1 dihydrochloride
- Pre-Queuosine 1 dihydrochloride
Useful catalog search terms
- CAS 86694-45-3
- PubChem CID 136229764
Physicochemical data
| Salt form | Dihydrochloride |
|---|---|
| Parent compound | 7-Aminomethyl-7-deazaguanine (preQ1) |
| InChIKey | WUMBRQKOLVTYTB-UHFFFAOYSA-N |
| PubChem CID | 136229764 |
| InChI | InChI=1S/C7H9N5O.2ClH/c8-1-3-2-10-5-4(3)6(13)12-7(9)11-5;;/h2H,1,8H2,(H4,9,10,11,12,13);2*1H |
| SMILES | C1=C(C2=C(N1)N=C(NC2=O)N)CN.Cl.Cl |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 7-Aminomethyl-7-deazaguanine dihydrochloride or its named chemical feature. Broader product-family guidance is maintained on the category page.
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