Arabino Phosphoramidites
2'-F-C(Ac)-ANA-CE-Phosphoramidite
Quick view. An N4-acetyl, 5'-O-DMTr-protected 2'-deoxy-2'-fluoroarabinocytidine CE phosphoramidite for oligonucleotide synthesis research. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-F-C(Ac)-ANA-CE-Phosphoramidite is classified as arabino phosphoramidites (Formula C41H49FN5O8P; molecular weight 789.84).
2'-F-C(Ac)-ANA-CE-Phosphoramidite — Protected 2'-fluoro-arabinocytidine phosphoramidite building block for oligonucleotide synthesis research.
For 2'-F-C(Ac)-ANA-CE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- DMTr-2'-ara-F-dC(Ac)-3'-CE-Phosphoramidite
- 2'-F-Ac-C-ANA-CE Phosphoramidite
- 5'-Dimethoxytrityl-N4-acetyl-2'-deoxy-2'-fluoroarabinocytidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
Physicochemical data
| Base protection | N4-acetyl cytosine |
|---|---|
| 5' protection | DMTr |
| Sugar configuration | 2'-deoxy-2'-fluoroarabino |
| 3' functionality | 2-cyanoethyl N,N-diisopropylphosphoramidite |
| Phosphorus configuration | Unspecified |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-F-C(Ac)-ANA-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Arabino Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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