Modified Nucleotides
Im-m7GDP
Quick view. Im-m7GDP is the P-imidazolide activated derivative of N7-methylguanosine 5'-diphosphate. CAS 531553-69-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
Im-m7GDP is classified as modified nucleotides (Formula C14H19N7O10P2; molecular weight 507.29).
Im-m7GDP — Activated m7GDP reagent for research involving chemical installation of m7G cap structures on 5'-phosphorylated RNA substrates.
For Im-m7GDP, capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
Names and search terms
Confirmed or normalized name variants
- m7GDP imidazolide
- 7-Methylguanosine 5'-diphosphate imidazolide
- M7-GDP-IMZ
Useful catalog search terms
- CAS 531553-69-2
Physicochemical data
| InChIKey | FSLUCUBHOZVVQK-QYVSTXNMSA-N |
|---|---|
| Physical form | White to off-white powder |
| Storage temperature | -20 C; keep dark and dry |
| Activation group | P-imidazolide |
| Nucleoside modification | N7-methylguanosine |
| PubChem CID | 136088880 |
| InChI | InChI=1S/C14H19N7O10P2/c1-19-6-21(11-8(19)12(24)18-14(15)17-11)13-10(23)9(22)7(30-13)4-29-33(27,28)31-32(25,26)20-3-2-16-5-20/h2-3,5-7,9-10,13,22-23H,4H2,1H3,(H4-,15,17,18,24,25,26,27,28)/t7-,9-,10-,13-/m1/s1 |
| SMILES | Cn1c[n+]([C@@H]2O[C@H](COP(=O)([O-])OP(=O)(O)n3ccnc3)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe Im-m7GDP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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