Modified Nucleosides
N6-Methyl-2'-beta-C-ethynyladenosine
Quick view. N6-Methyl-2'-beta-C-ethynyladenosine is listed for research-use inquiry under Modified Nucleosides. Its identity is controlled by the retained exact structure and product-form evidence because no public CAS Registry Number is assigned. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N6-Methyl-2'-beta-C-ethynyladenosine is classified as modified nucleosides (Formula C13H15N5O4; molecular weight 305.29).
N6-Methyl-2'-beta-C-ethynyladenosine is useful as a bioorthogonal handle for post-synthetic conjugation to fluorophores, affinity tags, surfaces, peptides or other functional payloads.
For N6-Methyl-2'-beta-C-ethynyladenosine, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Physicochemical data
| CAS status | No public CAS assigned |
|---|---|
| Identity control | Reviewed exact name, structure, and product form |
| InChIKey | KYXJGLMDBNYWOH-NHULRPGXSA-N |
| InChI | InChI=1S/C13H15N5O4/c1-3-13(21)9(20)7(4-19)22-12(13)18-6-17-8-10(14-2)15-5-16-11(8)18/h1,5-7,9,12,19-21H,4H2,2H3,(H,14,15,16)/t7-,9-,12-,13-/m1/s1 |
| SMILES | CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@]([C@@H]([C@H](O3)CO)O)(C#C)O |
| Canonical SMILES | CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@]([C@@H]([C@H](O3)CO)O)(C#C)O |
| PubChem CID | 170901698 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe N6-Methyl-2'-beta-C-ethynyladenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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