UNA Phosphoramidites
N2-Isobutyryl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-guanosine-3'-CE phosphoramidite
Quick view. A fully protected G-UNA building block comprising N2-isobutyryl-2',3'-seco-guanosine with 5'-O-DMTr, 2'-O-benzoyl, and 3'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 1120329-61-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
N2-Isobutyryl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-guanosine-3'-CE phosphoramidite is classified as una phosphoramidites (Formula C51H60N7O10P; molecular weight 962.05).
N2-Isobutyryl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-guanosine-3'-CE phosphoramidite — Identity-defined UNA-G(iBu) phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N2-Isobutyryl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-guanosine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- UNA-G(iBu)-CE phosphoramidite
- iBu-G-UNA-CE phosphoramidite
- N2-iBu-G-UNA phosphoramidite
Useful catalog search terms
- CAS 1120329-61-4
Physicochemical data
| InChIKey | PCZJDFIZVYBABW-WESQYFQMSA-N |
|---|---|
| Nucleobase | Guanine |
| Backbone | 2',3'-seco-guanosine (UNA-G) |
| Base protection | N2-Isobutyryl |
| Hydroxyl protection | 5'-O-DMTr and 2'-O-benzoyl |
| Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| InChI | InChI=1S/C51H60N7O10P/c1-34(2)47(59)55-50-54-46-45(48(60)56-50)53-33-57(46)44(32-64-49(61)37-16-11-9-12-17-37)68-43(31-67-69(66-29-15-28-52)58(35(3)4)36(5)6)30-65-51(38-18-13-10-14-19-38,39-20-24-41(62-7)25-21-39)40-22-26-42(63-8)27-23-40/h9-14,16-27,33-36,43-44H,15,29-32H2,1-8H3,(H2,54,55,56,59,60)/t43-,44-,69?/m1/s1 |
| SMILES | CC(N(P(OC[C@H](O[C@@H](N1C(N=C(N2)NC(C(C)C)=O)=C(N=C1)C2=O)COC(C3=CC=CC=C3)=O)COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)OCCC#N)C(C)C)C |
| Canonical SMILES | CC(N(P(OC[C@H](O[C@@H](N1C(N=C(N2)NC(C(C)C)=O)=C(N=C1)C2=O)COC(C3=CC=CC=C3)=O)COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)OCCC#N)C(C)C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
N6-Benzoyl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-adenosine-3'-CE phosphoramidite
UNA Phosphoramidites · CAS: 1120329-52-3
OR-UP-0002N4-Acetyl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-cytidine-3'-CE phosphoramidite
UNA Phosphoramidites · CAS: 1120329-56-7
OR-UP-00045'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite
UNA Phosphoramidites · CAS: 1120329-48-7
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.