Thio Phosphoramidites
3'-Thio-dI CE-Phosphoramidite
Quick view. A 5'-O-DMTr-protected 2'-deoxyinosine building block with a 3'-sulfur-linked cyanoethyl diisopropyl phosphoramidite group. CAS 1334533-56-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3'-Thio-dI CE-Phosphoramidite is classified as thio phosphoramidites (Formula C40H47N6O6PS; molecular weight 770.90 g/mol).
3'-Thio-dI CE-Phosphoramidite — Incorporation of a 3'-thioinosine modification during oligonucleotide synthesis
For 3'-Thio-dI CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-Thio-dI CEP
- 2'-Deoxy-5'-O-DMTr-inosine 3'-thio CE phosphoramidite
Useful catalog search terms
- 1334533-56-0
- ZKXFGLWRVAPHCL-RANQDXPPSA-N
Physicochemical data
| PubChem CID | 137279598 |
|---|---|
| IUPAC name | 3-[[(2R,3R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(6-oxo-1H-purin-9-yl)oxolan-3-yl]sulfanyl-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile |
| InChIKey | ZKXFGLWRVAPHCL-RANQDXPPSA-N |
| Stereochemistry note | Nucleoside stereochemistry is defined; phosphorus stereochemistry is unspecified. |
| InChI | InChI=1S/C40H47N6O6PS/c1-27(2)46(28(3)4)53(51-22-10-21-41)54-35-23-36(45-26-44-37-38(45)42-25-43-39(37)47)52-34(35)24-50-40(29-11-8-7-9-12-29,30-13-17-32(48-5)18-14-30)31-15-19-33(49-6)20-16-31/h7-9,11-20,25-28,34-36H,10,22-24H2,1-6H3,(H,42,43,47)/t34-,35-,36-,53?/m1/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)S[C@@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=CNC6=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
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Product-family literature
These publications provide peer-reviewed context for the Thio Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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