Modified Nucleotides
beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt
Quick view. A monosodium NAD+ analog bearing a 2'-deoxy-2'-fluoro-arabino modification on the nicotinamide-linked sugar. The adenine-linked ribose and pyrophosphate linkage remain present. CAS 133575-27-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt is classified as modified nucleotides (Formula C21H25FN7NaO13P2; molecular weight 687.40).
beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- Ara-F-NAD+ Sodium Salt
- beta-Ara-2'-F-NAD+ Sodium Salt
- beta-Ara-2'-Deoxy-2'-Fluoro-NAD+ Sodium Salt
Useful catalog search terms
- CAS 133575-27-6
Physicochemical data
| Salt form | Monosodium salt |
|---|---|
| Modification | 2'-deoxy-2'-fluoro-arabino substitution on the nicotinamide-linked sugar |
| Related parent PubChem CID | 44238635 |
| Related parent InChIKey | JSGNSBZQCQQLEF-OZCXFSBSSA-N |
| Dinucleotide linkage | Pyrophosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe beta-Ara-2'-Deoxy-2'-Fluoro-Nicotinamide Adenine Dinucleotide Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-OMe-GDP Disodium Salt
Modified Nucleotides · CAS: N/A
OR-INTE-00143'-OMe-GMP
Modified Nucleotides · CAS: 400806-41-9
OR-INTE-00153'-OMe-GMP TEA Salt
Modified Nucleotides · CAS: 860605-85-2
OR-INTE-0021Im-3'-OMe-GMP
Modified Nucleotides · CAS: 1005791-93-4
OR-INTE-0023Im-GDP
Modified Nucleotides · CAS: 1199264-75-9
OR-MN-0025(-)-Emtricitabine Triphosphate Tetrasodium Salt
Modified Nucleotides · CAS: 1188407-46-6
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.